Alzheimer?s disease (AD) is a neurodegenerative disease that, in its most common form, is found in people over age 65. Approximately 24 million people worldwide have dementia of which the majority (~60%) is due to AD.
Clinical signs of Alzheimer?s disease are characterized by progressive cognitive deterioration, together with declining activities of daily living and by neuropsychiatric symptoms or behavioral changes. It is the most common type of dementia. Plaques which contain misfolded peptides called amyloid beta (Aß) are formed in the brain many years before the clinical signs of Alzheimer's are observed. Together, these plaques and neurofibrillary tangles form the pathological hallmarks of the disease. Many AD cases in addition develop cortical synucleopathy. These features can only be discovered at autopsy and help to confirm the clinical diagnosis. Medications can help reduce the symptoms of the disease, but they cannot change the course of the underlying pathology.

Art der Einrichtung:
Universität

Arbeitsschwerpunkt:
Klinische Neurowissenschaften, Molekulare Neurobiologie

Anschrift:
Von-Siebold-Str. 5
37075 Göttingen
DE

Telefon:
0049 (0) 551-39 22 912

Homepage:
http://www.alzheimer-bayer.de/

Prof. Dr. Thomas Bayer

Position / Tätigkeit:
Leiter